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B006905 - BIOCHEMISTRY
Main information
Teaching Language
Course Content
Suggested readings
Learning Objectives
Prerequisites
Teaching Methods
Type of Assessment
Course program
Academic Year 2022-23
Coorte 2020 - 3-years First Cycle Degree (DM 270/04) in CHIMICA
Course year
Third year - Second Semester
Belonging Department
Chemistry "Ugo Schiff"
Course Type
Single education field course
Scientific Area
BIO/10 - BIOCHEMISTRY
Credits
6
Teaching Hours
48
Teaching Term
20/02/2023 ⇒ 12/06/2023
Attendance required
No
Type of Evaluation
Final Grade
Course Content
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Course program
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Lectureship
Teaching Language
Italian
Course Content
Structural organization of Eukaryotic and Prokaryotic cells. Metabolism of DNA and RNA. Proteins: biosynthesis, structure and functions. Allosteric proteins. The enzymes: kinetics, coenzymes, mechanism and regulation. Aminoacids, carbohydrates and lipids: structures, functions and metabolism. Biological membranes. The Tricarboxylic Acid Cycle and Oxidative Phosphorylation. The integration of metabolism.
Suggested readings (Search our library's catalogue)
Jeremy Berg, John L.Timoczcko, Lubert Stryer, "BIOCHIMICA" (Zanichelli) Donald Voet, Judith G. Voet, Charlotte W. Pratt, "FONDAMENTI DI BIOCHIMICA" (Zanichelli) David L. Nelson, Michael M. Cox, "I PRINCIPI DI BIOCHIMICA DI LEHNINGER" (Zanichelli) Garette-Grisham "PRINCIPI DI BIOCHIMICA" Ed PICCIN
Learning Objectives
Description of main molecular mechanisms of the living systems, included in a general functional, with the intention of presenting the many scientific aspects of biochemistry that are of great current interest for a chemist. At the end of the course the student will have acquired basic information about the major biomolecules and their function. It will also be able to understand what are the main biochemical mechanisms that regulate the metabolic processes of living organisms. Students can use the knowledge acquired to analyze the biochemical metabolic processes that are fundamental to life and understand how organisms react to both endogenous and exogenous stimuli.
Prerequisites
Courses required: none
Courses recommended: Organic chemistry I and Laboratory of Organic chemistry I
Courses recommended: Organic chemistry I and Laboratory of Organic chemistry I
Teaching Methods
Total number of hours for Lectures (hours): 48
Type of Assessment
Oral exam.
Course program
Eukaryotic and Prokaryotic cells. Chemical structures of Aminoacids. The peptide bond. Solid-phase peptide synthesis. Edman degradation. Structural organization of proteins: primary, secondary, tertiary and quaternary structures. Structure and function of hemoglobin: allosteric proteins. The enzymes: kinetics, coenzymes, inhibitors, catalytic mechanisms and regulation. Carbohydrates and lipids: structure and functions. Biological membranes. Active and passive transport through biological membranes. Nucleotides. Metabolism of DNA and RNA: duplication and transcription of DNA. Ribozymes. Protein biosynthesis. and lipids: structures, functions and metabolism. Metabolism: basic concepts. Signal Transduction. Glycolysis and Gluconeogenesis. Glycogen Metabolism. Pentose Phosphate Pathway. The Tricarboxylic Acid Cycle and Oxidative Phosphorylation. Fatty Acid Metabolism. Protein Turnover: Amino Acid Degradation and the Urea Cycle. The integration of metabolism.